Chlorphenesin

Chlorphenesin(104-29-0), sunan sinadarai shine 3- (4-chlorophenoxy) propane-1,2-diol, gabaɗaya ana haɗa shi ta hanyar amsawar p-chlorophenol tare da propylene oxide ko epichlorohydrin.Yana da wani m bakan antiseptik da antibacterial wakili, wanda yana da maganin antiseptik sakamako a kan Gram-tabbatacce kwayoyin cuta, Gram-korau kwayoyin, yeasts da molds.Kasashe da yankuna da yawa sun amince da amfani da shi a cikin kayan kwalliya kamar Turai, Amurka, Japan, da China.Iyakar amfani da aka yarda da yawancin dokoki da ka'idoji na ƙasa shine 0.3%.
ChlorphenesinBa a yi amfani da shi a asali azaman mai kiyayewa ba, amma azaman maganin rigakafi mai alaƙa da antigen wanda ke hana sakin histamine na IgE a cikin masana'antar harhada magunguna.A taƙaice, yana da anti-allergic.Tun daga shekarar 1967, masana'antar harhada magunguna sun yi nazarin amfani da chlorphenesin da penicillin don hana rashin lafiyar da penicillin ke haifarwa.Sai a shekara ta 1997 ne Faransawa ta gano chlorphenesin saboda tasirin sa na kashe-kashe da bacteriostatic da kuma neman haƙƙin mallaka.
1. Shin chlorphenesin ne mai shakatawa na tsoka?
Rahoton kimantawa ya yi nuni da cewa: sinadarin chlorphenesin na kwaskwarima ba shi da wani tasiri na kawar da tsoka.Kuma an ambaci shi sau da yawa a cikin rahoton: Ko da yake gajartawar Ingilishi na sinadarin chlorphenesin na magunguna da kuma sinadarin chlorphenesin na kwaskwarima duka biyun Chlorphenesin ne, bai kamata biyun su ruɗe ba.
2. Shin chlorphenesin yana fusatar da fata?
Ko ga mutane ko dabbobi, chlorphenesin ba shi da haushin fata a yawan adadin al'ada, kuma ba mai wayar da kan fata bane ko kuma mai daukar hoto.Akwai labarai huɗu ko biyar kawai game da rahotannin chlorphenesin da ke haifar da kumburin fata.Kuma akwai ƴan lokuta inda chlorphenesin da aka yi amfani da shi ya kai kashi 0.5% zuwa 1%, wanda ya zarce adadin da ake amfani da shi a cikin kayan kwalliya.A wasu lokuta da yawa, an ambaci cewa chlorphenesin yana kunshe a cikin dabarar, kuma babu wata shaida kai tsaye cewa chlorphenesin ya haifar da dermatitis.Idan aka yi la'akari da babban tushen amfani da chlorphenesin a cikin kayan kwalliya, wannan yuwuwar ba ta da komai.
3. Shin chlorphenesin zai shiga cikin jini?
Gwajin dabbobi ya nuna cewa wasu daga cikin chlorphenesin za su shiga cikin jini bayan sun hadu da fata.Mafi yawan sinadarin chlorphenesin da aka sha za a samu a cikin fitsari, kuma za a fitar da duka daga jiki cikin sa'o'i 96.Amma dukan tsari ba zai haifar da wani sakamako mai guba ba.
4. Shin Chlorphenescine zai rage rigakafi?
Ba zai yi ba.Chlorphenesin shine maganin rigakafi da ke da alaƙa da antigen mai juyawa.Da farko dai, chlorphenesin yana taka rawar da ya dace ne kawai idan aka haɗa shi da antigen da aka keɓe, kuma baya rage garkuwar jiki, kuma baya ƙara yawan kamuwa da cututtuka.Na biyu, bayan ƙarewar amfani, tasirin rigakafi na antigen da aka zaɓa zai ɓace, kuma ba za a sami sakamako mai dorewa ba.
5. Menene ƙarshe na ƙarshe na ƙimar aminci?
Dangane da aikace-aikacen da ake da su da kuma amfani da ƙima a cikin Amurka (wankewa 0.32%, nau'in mazaunin 0.30%), FDA ta yi imanin cewachlorphenesinyana da lafiya a matsayin kayan kariya na kwaskwarima.