Shin Dihydcooukin mai guba

Dhydrocooumin, kamshi, da aka yi amfani dashi a abinci, shima aka yi amfani da shi azaman madadin coumin, ana amfani dashi azaman dandano na kwaskwarima; Haɗaɗɗaɗa kirim, kwakwa, cinamon dandano; Hakanan ana amfani dashi azaman dandano na taba.

Shin Dihydcooukin mai guba

Dihydcoooin ba mai guba bane. Dihydcoomato kayan samfuri ne wanda aka samo a cikin launin rawaya vanilla. Ana shirya shi ta hanyar hydrogenation na coumin a gaban mai kara mai kara kuzari a 160-200 ℃ da kuma matsin lamba. Hakanan za'a iya amfani dashi azaman albarkatun ƙasa, hydroyyzed a cikin alkaline mai ruwa mai ruwa ruwa don samar da o-hydroxyphyphyphropionic da aka samu.

Yanayin ajiya

Rufe da duhu, adana shi a cikin wuri mai sanyi da bushe, sarari a cikin ganga yana da ƙananan yadda zai yiwu a ƙarƙashin izinin aminci, kuma yana cike da kariyar nitrogen. Store a cikin wani sanyi, gidan wanka. Ka nisanci wuta, ruwa. Ya kamata a adana dabam daga oxidizer, kar a haɗu da ajiya. Sanye take da kayan aiki da yawa na kayan wuta.

A cikin binciken Vitro

A cikin vitro enzymatic Assayi, Dihydcocooarkuin ya jawo maida hankali-dogaro da Sirt1 (IC50 na 208μm). Rage matakan Sirt1 Detantlases an lura da ko da a allurai micromar (85 ± 5.8 da 73 ± 13.7% aiki a 1.6μm da 8μm, bi da bi). Microtubule Sirt2 kuma an hana shi a cikin wani irin abu mai dogaro (IC50 na 29μm).

Bayan sa'o'i 24 na bayyanar, DihydrocoMarkin (1-5mmmm) ya ninka cytotoxicity a cikin tk6 sel layuka a cikin wani abu mai dogaro. Dihydcoakooin (1-5mmmm) ya karu apoptosis a layin sel a cikin layin Tk6 a cikin hanyar da aka dogara da lokaci a lokacin awa 6. A 5mm kashi dihydcocooumin ya ƙara apoptosis a lokacin awa 6 a cikin layin sel. Bayan lokaci mai shekaru 24, DohydrocoUOIN (1-5mmm) ya ninka P53 LYSETINE 373 da 382 Aceyations a cikin wani yanki mai dogaro a layin sel.