Pharmacodynamics na Chloroxylenol

Chloroxylenol, ko para-chloro-meta-xylenol (PCMX), sanannen wakili ne na ƙwayoyin cuta da bakararre.Wani kayan tsaftacewa ne da ake amfani dashi a gidan wasan kwaikwayo na asibiti don tsaftace kayan aikin tiyata.

Chloroxylenol yana daya daga cikin sinadarai masu aiki da ake amfani da su wajen yin sabulun maganin kashe kwayoyin cuta.Hakanan, aikace-aikacen sa sun yanke ƙetaren likita da na gida azaman maganin kashe ƙwayoyin cuta.

Bisa ga Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya, chloroxylenol mai saurin kamuwa da nau'in kwayoyin cuta da aka sani da Gram-positive, an rubuta shi sosai.

Koyaya, kuna buƙatar wakili mai kyau na ƙwayoyin cuta da ƙwayoyin cuta don bukatun gidan ku da na asibiti, to dole ne ku tuntuɓi wani sanannechloroxylenolmasana'anta.

Alamar Pharmacological na Chloroxylenol

Aikace-aikacen Chloroxylenol suna da kyau a cikin filin likita.

An yi amfani da shi a baya wajen maganin cututtukan fata kamar su karce, yanke, cizon dabbobi, tsatsa, da tsabtace hannu.

Pharmacodynamics na Chloroxylenol

Chloroxylenolshine maye gurbin phenol, ma'ana yana da ƙungiyar hydroxyl a cikin tsarinsa.

Aikace-aikacen sa sananne ne tsawon shekaru a matsayin ɗayan abubuwan da ke aiki na samfuran kashe ƙwayoyin cuta.Ana gabatar da aikace-aikacen sa a wajen tantanin halitta.

Ayyukan antimicrobial a ƙaramin adadin zuwa rukuni na ƙwayoyin cuta an ruwaito.

Tsarin Aiki

Kasancewar ƙungiyoyin hydroxyl a cikin tsarinsa yana da matukar mahimmanci, musamman lokacin da za a bayyana yuwuwar sa na harhada magunguna.

Ana tsammanin ƙungiyar hydroxyl ta haɗa zuwa wuraren haɗin furotin, wanda shine, bi da bi, yana taimakawa wajen hana ƙwayoyin cuta da suke kaiwa hari.

Chloroxylenol yana shiga cikin kwayar cutar kwayar cutar don kaiwa hari tare da isassun enzymes da sunadarai.Lokacin da aka yi haka, yana kashe ayyukan tantanin halitta.

Zai kai matakin da ake amfani da adadin Chloroxylenol mai yawa ga ƙwayoyin jini wanda ke haifar da mutuwarsu.

Metabolism na Chloroxylenol

Don cikakkun takaddun Chloroxylenol a matsayin wakili na kwayan cuta da na kashe ƙwayoyin cuta, an yi amfani da dabbobi don cikakken nazarin ayyukan iyawar sa.

Binciken dabba ya nuna cewa saboda amfani da Chloroxylenol na fata, yawan nutsewa ya yi sauri cikin sa'o'i biyu na farko.

An kuma lura cewa sinadarin da aka baiwa dabbobin an fitar da fitsari ne ta cikin koda tare da cire shi gaba daya cikin tafiyar sa'o'i 24.

Mahimmin ɓangaren da aka gano a cikin samfurin da aka lalata ya haɗa da glucuronides da sulfates.

Yawancin labaran bincike game da Chloroxylenol idan aka kwatanta ayyukansa zuwa sanannun kuma mai kula da kwayoyin cutar da ake kira triclosan.Rahoton ya nuna cewa glucuronides ma sun kasance wani ɓangare na samfurin da aka lalata a cikin ƙirar ɗan adam.

Bugu da ƙari, daga binciken samfurin ɗan adam, an ɗauka cewa kowane 5 MG da aka ɗauka a cikin jiki zai iya yin fitsari har zuwa 14% na glucuronic acid da sulfuric acid a cikin kwanaki uku.

Duk da haka, duk wani adadin Chloroxylenol da aka ɗauka a cikin tsarin daga baya hanta za ta narkar da shi kuma a fitar da shi azaman sulfate da abubuwan glucuronic.

Hanyar Kawarwa

Kamar yadda ake iya gani a sama daga binciken da aka gudanar tare da Chloroxylenol ya nuna cewa babbar hanyar cire chloroxylenol daga tsarin bayan gudanarwa shine ta fitsari.

Ko da yake, ana ɗaukar ƙaramin adadin yana cikin bile kuma kaɗan kaɗan a cikin iskar da aka hura.

Shin kuna buƙatar Chloroxylenol?

Da kyaudanna nanyau donChloroxylenoldon duk kayan aikin antiseptik da masu kashe ƙwayoyin cuta, kuma za mu yi farin cikin yin haɗin gwiwa tare da ku don samfuran mafi kyau.